Grim Fandango. Despite the weird tank controls, it created such an amazing world - and all in a point-and-click adventure. My home PC is named Manny, our NAS is Eva, the router/firewall is Glottis, and so on.
Also, Psychonauts. Just a perfect 3D platformer.
I have. In fact, I backed the development of it.
Definitely worth playing. Maybe a bit less memorable than the original, but also a bit more consistent. There are no huge difficulty spikes like the Meat Circus in the original.
The story is a bit more complex, and a bit more muted. Most of the levels are less memorable. But absolutely worth the time to play and enjoy.